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Buy Fentanyl Online is roughly 100 times more potent than morphine and 50 times more potent than heroin. In fact, it is the most potent opioid pain reliever available for use in medical treatment.
Although fentanyl is considered safe and effective when used and monitored in a medical setting, it carries a high abuse potential.
Fentanyl analogs – designer drugs nearly identical to the original – can be manufactured and mixed with or substituted for heroin. Because fentanyl and its analogs are incredibly potent, accidental overdoses and deaths are increasingly common trusted Sources.
Fentanyl is sometimes mixed with heroin. Because it is much more potent than heroin, there is a hugely increased risk of overdose and death.
In this article, we will discuss the medical uses of fentanyl and its side effects. We will also cover abuse of fentanyl, addiction, and overdoses.
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Here are some key points about fentanyl. More detail and supporting information are in the main article.
- Fentanyl is a potent synthetic opioid that is very effective at relieving moderate to severe chronic pain.
- Oral formulations of fentanyl contain an amount of the drug that can be fatal to a child.
- The difference between a therapeutic dose and a deadly dose of fentanyl is very small.
- There are many illegal analogs and derivatives of fentanyl that are much stronger than the prescription version.
- Recreational users often use fentanyl as a substitute for heroin.
What is fentanyl?
Fentanyl is around 100 times more potent than morphine.
Fentanyl binds to the body’s opioid receptors, increasing dopamine levels in the central nervous system.
The increase in dopamine produces a state of relaxation, relieves pain, decreases the perception of suffering, and promotes a feeling of well-being (euphoria).
It is used to manage pain during surgery; it is also used to treat moderate-to-severe chronic pain syndromes in people who are already physically tolerant to opiates.
Fentanyl depresses the respiratory centers and the cough reflex and constricts the pupils. It can work within minutes to relieve pain and produce sedation. Fentanyl has a short duration of effect – just 30-90 minutes.
Fentanyl affects everyone differently. The effects are dependent on an individual’s size, weight, the overall state of health, the amount that is taken, whether fentanyl is taken in combination with other drugs, and whether the person is used to taking opioids.
Medically prescribed fentanyl is available in a variety of formulations, including lozenges, lollipops, oral and nasal sprays, and injections.
Fentanyl abuse and heroin
Abuse of fentanyl initially appeared in the 1970s and has increased in recent years.
The drug can be obtained by diverting from legitimate medical supplies, or it can be manufactured in illegal laboratories.
Even discarded fentanyl patches can still contain significant amounts of the drug.
Abusers remove the gel contents from discarded patches and may eat it, place it under the tongue, smoke it, or even inject it.
Fentanyl analogs produced in illicit laboratories maybe hundreds of times more potent than street heroin and tend to produce significantly more respiratory depression, making them even more dangerous to users than heroin.
Individuals using heroin or cocaine, or in recovery for a drug use disorder may not know that the potency of street-sold heroin and cocaine can be significantly enhanced by adding fentanyl. Because the potency of such drugs is not known, and they are not told about the addition of fentanyl, any illicit drug use – even a reduced dose – can result in accidental overdose or death.
Fentanyl may be used orally, smoked, snorted, or injected and no one method of use is safer than another.
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Medical uses Of Fentanyl
Medical uses for fentanyl include:
- Anesthesia for patients undergoing heart surgery or for patients with poor heart function.
- Management of breakthrough cancer pain in patients who are already receiving opioid medication for underlying, persistent pain.
- Pain management in patients who have persistent, moderate-to-severe chronic pain requiring continuous, around-the-clock opioids.
- In patients who are already taking narcotic analgesics or who are already opioid-tolerant.
- It can be used intravenously, intramuscularly, spinally, or as an epidural (into space at the bottom of the spinal cord).
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Older patients are more likely than younger individuals to experience adverse effects, especially the respiratory depressant effects of fentanyl. Extreme caution and monitoring must be followed with this age group.
Side effects of fentanyl include:
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As with any opiate, there is a risk of dependency, tolerance, abuse, and addiction to fentanyl use. Physical dependence results in withdrawal symptoms when individuals abruptly stop taking the drug.
Withdrawal symptoms usually start within 12 hours of the last dose of fentanyl and can last 1 week or more. An individual in withdrawal may experience:
- dilated pupils
- vomiting and diarrhea
- a runny nose
- hot and cold flashes
- severe generalized pain
Fentanyl users swiftly develop a tolerance to high doses, meaning that more of the drug is needed for users to achieve the desired effect.
Repeated opioid use often results in addiction – a chronic relapsing disease that goes beyond physical dependence and is characterized by uncontrollable drug-seeking behavior despite harmful and negative consequences. Seeking and using the drug of choice becomes the primary purpose in life.
Treatment for fentanyl addiction is the same as for any opioid use disorder and depends on the severity of the addiction. Treatment may include inpatient or outpatient detox, medication treatments for managing cravings and relapse, and residential and outpatient behavioral treatment programs.
Fentanyl use can result in accidental death even with just one dose, especially if it is taken incorrectly or by someone other than the person with the prescription.
Signs and symptoms of a fentanyl overdose include:
- slow or shallow breathing
- slow heartbeat
- severe sleepiness
- cold, clammy skin
- trouble walking or talking
- feeling faint, dizzy, or confused
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Fentanyl is sometimes used as a substitute for heroin in opioid-dependent individuals. However, it is a very dangerous substitute because of its marked potency and the inability for users to gauge dosages, resulting in frequent deadly overdoses.
Pure fentanyl powder is very difficult to dilute appropriately, often resulting in a dangerously strong mixture; it can be deadly even for people who have a high opioid tolerance. In some cases, death occurs so quickly that users are found with a needle still in the site of injection.
The minimum lethal dosage of Fentanyl is estimated to be 250 ug (micrograms). Many fatal overdoses thought to be from heroin are actually due to fentanyl; coroners’ offices and state crime laboratories do not test for fentanyl or its analogs unless given a specific reason to do so.
Fentanyl overdoses should be treated immediately with naloxone, an opiate antagonist that knocks opiates from the brain’s receptors. Although fentanyl overdoses can be reversed with naloxone, because of the high potency of non-pharmaceutical fentanyl, higher or multiple doses of nalo xone may be required to revive an individual.
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Fentanyl is an extremely potent opioid that offers significant pain relief to those who suffer from severe acute or chronic pain conditions but is also capable of causing considerable harm or death to individuals who misuse or are accidentally exposed.
Some patients and healthcare providers may not be fully aware of the dangers of this very strong narcotic. All of society, including families, schools, the medical community, law enforcement, and government officials should be aware of the potentially lethal outcomes of improper medical and illicit fentanyl use.